L-Carnitine is an amino acid derivative central to mitochondrial fatty-acid transport and energy metabolism research. Supplied as a ready-to-use 20mL solution.
| Contents | 20mL solution vial |
| Form | Ready-to-use solution |
| Storage | Cool and dry, away from light |
| Batch | COA available on request |
L-Carnitine is an amino acid derivative central to mitochondrial fatty-acid transport and energy metabolism research. Supplied as a ready-to-use 20mL solution.
L-Carnitine is a quaternary ammonium compound derived from lysine and methionine. It is not a peptide. Its established biological role is as the obligatory carrier that transports long-chain fatty acids across the inner mitochondrial membrane so they can undergo beta-oxidation.
Without carnitine, long-chain fatty acids cannot reach the mitochondrial matrix where fat oxidation occurs — which is why it appears in nearly every discussion of fatty-acid energy metabolism.
Supplied as a ready-to-use solution. For laboratory research use only. Not for human consumption.
Carnitine palmitoyltransferase I attaches fatty acyl groups to carnitine on the outer mitochondrial membrane; a translocase moves the complex across; CPT II releases the fatty acid inside. This shuttle is the rate-limiting step of long-chain fatty-acid oxidation.
A large applied literature examines carnitine supplementation in exercise contexts, with endpoints including markers of muscle damage and recovery following exertion.
Studies have examined whether raising muscle carnitine content alters substrate selection between fat and carbohydrate, and under what conditions the shuttle is actually rate-limiting.
Carnitine conjugates are widely used as metabolic biomarkers; acyl-carnitine profiling is a standard analytical technique for characterising fatty-acid oxidation disorders.
Carnitine has a substantial human research literature, including systematic reviews. Material supplied here is a research reagent, not an approved medicine.
Concentration is set by the volume of diluent added. For a 200mg vial, 1mL of bacteriostatic water yields 200mg/mL. Calculate the working concentration your protocol requires rather than following a generic figure.
| State | Temperature | Practical shelf life |
|---|---|---|
| Lyophilized, sealed | −20 °C | 24+ months |
| Lyophilized, sealed | 2–8 °C | ~12 months |
| Lyophilized, sealed | Room temperature | Weeks — transit only |
| Reconstituted, bacteriostatic water | 2–8 °C | ~3–4 weeks |
| Reconstituted, sterile water | 2–8 °C | Same session |
Lyophilized peptide is stable enough to survive shipping at ambient temperature, which is why cold-chain courier service is not required for transit. Long-term storage is a different matter — material intended to be held for months belongs in a freezer.
Protect from light, and avoid repeated freeze-thaw cycles. Each cycle causes measurable degradation, so dividing a reconstituted stock into single-use aliquots before freezing is preferable to thawing and refreezing one vial repeatedly.
Every lot is tested by an independent laboratory using two orthogonal methods. HPLC (high-performance liquid chromatography) establishes purity as a percentage of total peptide content, separating the target compound from truncated sequences and synthesis by-products. LC-MS (liquid chromatography–mass spectrometry) confirms molecular identity by mass.
Both matter. Purity alone is insufficient — a 99% pure sample of the wrong compound is still the wrong compound. Together the two tests establish identity and quality, which is why L-Carnitine is released only after both pass.
The certificate of analysis references the lot number printed on your vial label. Request the COA for your lot at sales@pepsdepot.com.
Peer-reviewed studies indexed in PubMed. Each links to the abstract and, where a free copy exists, to the full text. We link primary sources rather than summarising them second-hand.
Compounds studied alongside this one, or acting through related pathways.
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