KLOW 80mg (Single Vial)
KLOW is our extended multi-peptide complex, pairing the GLOW base with additional KPV for a broader research profile across tissue repair and inflammatory pathways.
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Product Details
| Purity | ≥99% (LC-MS verified) |
| Form | Lyophilized powder, preservative free |
| Storage | Cool and dry; refrigerate after reconstitution |
| Batch | COA available on request |
Why Choose KLOW 80mg (Single Vial)?
KLOW is our extended multi-peptide complex, pairing the GLOW base with additional KPV for a broader research profile across tissue repair and inflammatory pathways.
Key Benefits
- KPV + GHK-Cu + BPC-157 + TB-500 complex
- Third-party tested — COA available on request
- Lyophilized, preservative free
- Ships from the USA in discreet packaging
About KLOW 80mg (Single Vial)
KLOW is a four-peptide preparation — the GLOW base of GHK-Cu, BPC-157 and TB-500, with KPV added. KPV is a tripeptide corresponding to the C-terminal fragment of alpha-melanocyte-stimulating hormone, studied for activity in inflammatory signalling pathways.
The addition broadens the research profile of the preparation beyond matrix and migration mechanisms to include inflammatory pathway work. The stated milligram figure is combined peptide content across all four components.
Supplied for laboratory research use only. Not for human consumption.
Research background
The KPV addition
KPV (lysine-proline-valine) is the C-terminal tripeptide of alpha-MSH. Research has examined it in models of inflammatory signalling, where it appears to retain activity associated with the parent hormone without the pigmentary effects of full-length alpha-MSH.
GHK-Cu component
Copper-binding tripeptide associated with matrix remodelling and collagen synthesis in culture.
BPC-157 component
Associated with angiogenic signalling and nitric-oxide pathway modulation.
TB-500 component
Actin-binding fragment associated with cell migration in wound-coverage models.
Research on the four-component combination specifically is limited; the literature concerns the individual peptides. None is an approved drug.
Reconstitution
- Equilibrate firstAllow the vial to reach room temperature before opening. Introducing solvent into a cold vial promotes condensation, which affects both concentration accuracy and stability.
- Select the diluentBacteriostatic water — sterile water with 0.9% benzyl alcohol — is standard where the solution will be held for more than a few days. Plain sterile water is appropriate only for single-session use with no storage.
- Add slowly, down the wallDirect the solvent against the inner wall of the vial rather than onto the powder. A stream striking the lyophilized cake causes localized shear that can denature peptide chains.
- Do not shakeSwirl gently, or simply let the vial stand. Agitation introduces air and mechanical stress, and both degrade peptides. Full dissolution usually takes a minute or two.
- Inspect before useA correctly reconstituted solution is clear and colourless. Cloudiness, visible particulate or discolouration indicates a problem with the material or the diluent.
Concentration is set by the volume of diluent added. For a 80mg vial, 5mL of bacteriostatic water yields 16mg/mL. Calculate the working concentration your protocol requires rather than following a generic figure.
Storage and stability
| State | Temperature | Practical shelf life |
|---|---|---|
| Lyophilized, sealed | −20 °C | 24+ months |
| Lyophilized, sealed | 2–8 °C | ~12 months |
| Lyophilized, sealed | Room temperature | Weeks — transit only |
| Reconstituted, bacteriostatic water | 2–8 °C | ~3–4 weeks |
| Reconstituted, sterile water | 2–8 °C | Same session |
Lyophilized peptide is stable enough to survive shipping at ambient temperature, which is why cold-chain courier service is not required for transit. Long-term storage is a different matter — material intended to be held for months belongs in a freezer.
Protect from light, and avoid repeated freeze-thaw cycles. Each cycle causes measurable degradation, so dividing a reconstituted stock into single-use aliquots before freezing is preferable to thawing and refreezing one vial repeatedly.
Purity and verification
Every lot is tested by an independent laboratory using two orthogonal methods. HPLC (high-performance liquid chromatography) establishes purity as a percentage of total peptide content, separating the target compound from truncated sequences and synthesis by-products. LC-MS (liquid chromatography–mass spectrometry) confirms molecular identity by mass.
Both matter. Purity alone is insufficient — a 99% pure sample of the wrong compound is still the wrong compound. Together the two tests establish identity and quality, which is why KLOW is released only after both pass.
The certificate of analysis references the lot number printed on your vial label. Request the COA for your lot at sales@pepsdepot.com.
Published research
Peer-reviewed studies indexed in PubMed. Each links to the abstract and, where a free copy exists, to the full text. We link primary sources rather than summarising them second-hand.
Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic Application
The glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
Frequently asked questions
What is the difference between KLOW and GLOW?
What is KPV?
Will the solution be coloured?
Does this need refrigerated shipping?
Is a certificate of analysis available?
Is KLOW approved for human use?
Customer reviews
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Compounds studied alongside this one, or acting through related pathways.
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